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Raltitrexed

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Formula: C21H22N4O6S
CAS: 112887-68-0
search Element: raltitrexed
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Identification

Structural Formula
Raltitrexed
CAS:
112887-68-0
EINECS:
Molecular Formula:
C21H22N4O6S
MDL:
MFCD00864168
SMILES:
CC1=NC(=O)C2=CC(C=CC2=N1)CN(C)C3=CC=C(S3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Synonym:


Description

Raltitrexed is a folate-based inhibitor of thymidylate synthase (TS) that is rapidly and extensively metabolized to its more potent polyglutamate derivatives. Raltitrexed is an inhibitor of DHFR.


Suppliers

Ambeed, Inc.
A222261
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
+
H&Z Industry Co.,Ltd
HIC220880
+
Chemvon Biotechnology Co. Ltd.
CBC3301320
+
Xiamen Equation Chemical Co.,Ltd
XECC3521760
+
CSNpharm, Inc.
CSN11829
Pharmacore Co., Limited
PL253759
Hefei Hirisun Pharmatech Co., Ltd
HR010416
+
AK Scientific, Inc.
AS209627
+
Simagchem Corporation
SC231693
+
Xingrui Industry Co., Limited
XIL3191276
+
BOC Sciences
BS132396
+
Leap Chem Co., Ltd
LC198594
+
Santa Cruz Biotechnology, Inc.
219933
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
+
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CAS equal suppliers

(S)-2-(5-(Methyl((2-methyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)amino)thiophene-2-carboxamido)pentanedioic acid
BLD Pharmatech Ltd
BP3078092340

Prices & Availability




Data is processed


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Properties for Raltitrexed

Molecular Weight:
458.49 g·mol−1
Density:
~1.5 g/cm3 (Predicted)
Melting point:
174-179° C
Solubility:
Soluble in water (<1 mg/ml at 25° C), DMSO (92 mg/ml at 25° C), methanol (warmed), and ethanol (<1 mg/ml at 25° C).
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

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Alternative Distributors of [Raltitrexed]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | World Biopharma Group Limited / World (Jiangsu) Industry Co.,Ltd | Molekula GmbH | Dalian Richon Chem Co., Ltd. | CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | 3B Scientific Corporation | Hangzhou Think Chemical Co., Ltd. | Jinan Jinao Chemical Development Co., Ltd. | Taizhou Bolon Pharmachem Co.,Ltd.. / Bolon Pharm & Chem Co., Ltd. | China Risesun Group Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | SYNCHEM OHG | Shanghai Richem International Co., Ltd. | Atomole Scientific Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Watson International Ltd | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC.

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