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Ritonavir

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Formula: C37H48N6O5S2
CAS: 155213-67-5
search Element: ritonavir

Identification

Structural Formula
Ritonavir
CAS:
155213-67-5
EINECS:
Molecular Formula:
C37H48N6O5S2
MDL:
MFCD00927142
SMILES:
CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
Synonym:
ritona ; ritonavir ; abbott 84538 ; nsc 693184 ; a 84538 ; norvi ; abt-538 ; norvir ; ritonavi ; litonavir


Description

Ritonavir is an inhibitor of HIV-1 protease used to treat HIV infection and AIDS. Currently rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, CYP3A4 (cytochrome P450-3A4).


Suppliers

Ambeed, Inc.
A547820
Aozeal Certified Standards (AOCS), Inc.
R0018.00
H&Z Industry Co.,Ltd
HIC180720
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT4592295
Alpha Biopharmaceuticals Co., Ltd.
AB306918
Arcadia Biotechnology
AB189567
Kingreat Chemistry Company Limited
KCCL3061530
Xiamen Equation Chemical Co.,Ltd
XECC2881440
Sancai Industry Co.,Ltd.
SIC216864
CSNpharm, Inc.
CSN13587
Hangzhou Keying Chem Co., Ltd.
HKC2701080
Hangzhou Lingrui Chemical Co., Ltd.
HLC3151260
Sigma-Aldrich International GmbH
SI288864
scienTEST - bioKEMIX GmbH
S-B225900
Carbone Scientific Co., Ltd.
CS252756
Hefei Hirisun Pharmatech Co., Ltd
HR011054
CM Fine Chemicals
CFC153612
AK Scientific, Inc.
AS171513
Xingrui Industry Co., Limited
XIL2611044
BOC Sciences
BS108324
Amadis Chemical Company Limited
ACCL2791395
Leap Chem Co., Ltd
LC162486
Santa Cruz Biotechnology, Inc.
208310
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CAS equal suppliers

Ritonavir d6
Salsbury Chemicals, Inc.
SC5761728
Ritonavir - Labeled d6
Santa Cruz Biotechnology, Inc.
sc-355967
Thiazol-5-ylmethyl ((2S,3S,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate
BLD Pharmatech Ltd
BP64170192510

Prices & Availability




Data is processed


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Properties for Ritonavir

Molecular Weight:
720.96 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
120-122 °C
Boiling point:
~947° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol, water (partly), ethanol (~5 mg/ml), DMF (~15 mg/ml), and DMSO (100 mg/mL at 25° C).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/38 - Irritating to eyes and skin
R41 - Risk of serious damage to eyes
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S37/39 - Wear suitable gloves and eye/face protection
S39 - Wear eye/face protection
Hazard Symbols:
Xi, Xn
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Ritonavir]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Discovery Fine Chemicals Limited | 3B Scientific Corporation | Toptechlab Pharmaceutical Co., Ltd. | Shanghai Honghao Chemicals Co., Ltd. | Unispec Chemicals Co. | ShangHai Biochempartner Co., Ltd. | Lonzeal Pharmaceuticals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Vosun Chemical Co.,Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Lanospharma Laboratories Co., Ltd. | Evershine Chemical Co.,Ltd. | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Watson International Ltd | BOC Sciences | Wolves R&D Chemicals | Changzhou Koye Chemical Co., Ltd | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Green Fine Chemical (Shanghai) Co., Ltd. | scienTEST | Wanko Chemical Co., Ltd.

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