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Rosmarinic Acid

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Formula: C18H16O8
CAS: 537-15-5
search Element: rosmarinic acid

Identification

Structural Formula
Rosmarinic Acid
CAS:
537-15-5
EINECS:
Molecular Formula:
C18H16O8
MDL:
SMILES:
C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
Synonym:
[r-(+)]-alpha-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid ; rosmarinic acid ; 3-(3,4-dihydroxyphenyl)-2-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]propanoic acid ; (r)-alpha-[[3-(3,4-dihydroxyphenyl)-1-oxo-2e-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid ; 3-(3,4-dihydroxyphenyl)acrylic acid-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester ; rosmarinate ; (r)-2-(3,4-dihydroxycinnamoyloxy)-3-(3,4-dihydroxyphenyl)lactic acid ; (2r)-3-(3,4-dihydroxyphenyl)-2-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-propanoic acid ; (r)-a-[3-(3,4-dihydroxyphenyl)-1-oxo-2e-propenyl]oxy-3,4-dihydroxybenzenepropanoic acid


Description

Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.


Suppliers

Autech Industry Co.,Limited
AIC8103240
Tianjin YR Chemspec Technology Co.,Ltd.
TYCTC11707020
H&Z Industry Co.,Ltd
HIC6002400
Chemlyte Solutions
CS5401620
Boehringer Ingelheim GmbH
BI7502250
Wuhan Atomole Chemicals Co., Ltd.
AT-4008
Sancai Industry Co.,Ltd.
SIC7202880
CSNpharm, Inc.
CSN16186
Finetech Industry Limited
FIL7503000
Pharmacore Co., Limited
PL6902070
Acinopeptide Co., Ltd.
A6601320
CM Fine Chemicals
CFC5102040
CM Fine Chemicals
CFC5102040
Capot Chemical Co., Ltd.
45077
Leap Chem Co., Ltd
LC5401620
Santa Cruz Biotechnology, Inc.
202796
Dayang Chem (Hangzhou) Co.,Ltd.
DC9303720
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CAS equal suppliers

Rosemary extract
Arakato Development Ltd
AD7362208
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FUDAW INDUSTRY LTD
FI5761728
Benzenepropanoic acid, a-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-
Gihi Chemicals Co., Limited
GCL29160116640
alpha-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-benzenepropanoic acid
Gihi Chemicals Co., Limited
GCL27324109296

Prices & Availability




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Properties for Rosmarinic Acid

Molecular Weight:
360.31 g·mol−1
Melting point:
171-175 °C(lit.)
Solubility:
Soluble in water (100 mM), ethanol (~25 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (pH 7.2) (~15 mg/ml).
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Safety & Transport Information

Risk Codes:
R36/38 - Irritating to eyes and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37/39 - Wear suitable gloves and eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [Rosmarinic Acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | CMS Chemicals Ltd. | ABCR GmbH & Co. KG | Chengdu Biopurify Phytochemicals Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Brightol International Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinjiangchem Corporation | Chemland International Co.,Ltd. | Chengdu Conut Intl. Co., Ltd. | Jinan Haohua Industry Co., Ltd.

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