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SAG

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Formula: C28H28ClN3OS
CAS: 912545-86-9
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Identification

Structural Formula
SAG
CAS:
912545-86-9
EINECS:
Molecular Formula:
C28H28ClN3OS
MDL:
MFCD22581513
SMILES:
CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl
Synonym:
3-chloro-n-((1r,4r)-4-(methylamino)cyclohexyl)-n-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide ; 3-chloro-n-[trans-4-(methylamino)cyclohexyl]-n-[[3-(4-pyridinyl)phenyl]methyl]- ; smoothened agonist (sag) ; 3-chloro-n-[trans-4-(methylamino)cyclohexyl]-n-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide ; sag ; sag.hci ; sag (smo agonist) ; sag(smoothened agonist) ; smoothened agonist (sag) hcl ; sag (cyclopamine antagonist)


Description

SAG is a potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function.


Suppliers

Aea.ltd
A2142
+
Iris Biotech GmbH
LS-1270.0000
+
Santa Cruz Biotechnology, Inc.
212905
Dayang Chem (Hangzhou) Co.,Ltd.
DC93372
+
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CAS equal suppliers

3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide
Leap Chem Co., Ltd
LC2772083160
3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide
Finipharma Ltd
F2156043120

Prices & Availability




Data is processed


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Properties for SAG

Molecular Weight:
490.06 g·mol−1
Melting point:
45-50° C
Solubility:
Soluble in DMSO (10 mg/mL), and sparingly soluble in water (acidification with HCl increases water solubility).
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Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [SAG]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

D&P Global Chemical Co., Ltd

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Downloads

Mol File:
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MSDS:
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