Spironolactone | CAS 52-01-7 | Chemical-Suppliers

Element: spironolactone

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C-S » Chemicals » spironolactone-PX68498

Identification

Spironolactone

CAS:

52-01-7

EINECS:

200-133-6

Molecular Formula:

C₂₄H₃₂O₄S

MDL:

MFCD00082250

SMILES:

CC(=O)SC1CC2=CC(=O)CC[C@]2(C)C2CC[C@@]3(C)C(CC[C@@]33CCC(=O)O3)[C@H]12

Synonym:

acelat ; aldopur ; osiren ; altex ; dira ; alderon ; sc9420 ; osyrol ; almatol ; aldace

Description

Spironolactone is a competitive MCR (mineralocorticoid receptor) antagonist that exhibits antihypertensive activity in vivo. Also displays antiandrogen activity and inhibits steroid hormone biosynthesis. Spironolactone is an inhibitor of AR.

Suppliers

Shandong Minglang Chemical Co., Ltd

SMC4901960

H&Z Industry Co.,Ltd

HIC2801120

Shandong SanYoung Industry Co., Ltd

SSI4901960

Nantong Xindao Biotech Ltd

NXB3641456

Aozeal Certified Standards (AOCS), Inc.

S0033.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI9663864

Indofine Chemical Co, Inc.

023554

Guangzhou Topwork Chemical Co., Ltd.

GTC5042016

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT7143570

AXO Industry SA

AIS210840

Alfa (A Johnson Matthey Company)

A4481344

Caesar & Loretz GmbH

CL280840

Xiamen Equation Chemical Co.,Ltd

XECC4482240

Sancai Industry Co.,Ltd.

SIC3361344

Arakato Development Ltd

AD322966

Aecochem Corp.

AC196588

Hangzhou Keying Chem Co., Ltd.

HKC4201680

Sigma-Aldrich International GmbH

SI4481344

scienTEST - bioKEMIX GmbH

S-B3501400

AK Scientific, Inc.

AS266798

Leap Chem Co., Ltd

LC252756

Santa Cruz Biotechnology, Inc.

204294

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CAS equal suppliers

Aldactone

Salsbury Chemicals, Inc.

SC216648

Spironolactone, 99%

Acros Organics BVBA

AOB3611444

17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate

Chemieliva Pharmaceutical Co., Ltd.

CP2716081480

17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate

Wanko Chemical Co., Ltd.

WC1862455872

Prices & Availability

Data is processed

Properties for Spironolactone

Molecular Weight:

416.57 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

207-208 °C(lit.)

Boiling point:

~597.0° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (0.022 mg/ml at 25° C), ethanol (50 mM), methanol, DMSO (100 mM), and chloroform (50 mg/ml).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
R60 - May impair fertility

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

T, Xn, Xi

Storage temperature :

Store at RT

Alternative Distributors of [Spironolactone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified