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3-(3-tert-Butyl-4-methoxybenzylidenyl)­indolin-2-one

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Formula: C20H21NO2
CAS: 293302-19-9

Identification

Structural Formula
3-(3-tert-Butyl-4-methoxybenzylidenyl)­indolin-2-one
CAS:
293302-19-9
EINECS:
Molecular Formula:
C20H21NO2
MDL:
SMILES:
COc1ccc(/C=C/2C(=O)Nc3ccccc23)cc1C(C)(C)C
Synonym:
3-(3-tert-butyl-4-methoxybenzylidenyl)indolin-2-one


Description

3-(3-tert-Butyl-4-methoxybenzylidenyl)indolin-2-one is a selective receptor tyrosine kinase (RTK) inhibitor. Inhibits HER-2 RTK (IC50 ~13μM). 3-(3-tert-Butyl-4-methoxybenzylidenyl)indolin-2-one consists predominantly of the E-isomer, contains ~10% of the Z-isomer.


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3-(3-tert-Butyl-4-methoxybenzylidenyl)indolin-2-one
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Properties for 3-(3-tert-Butyl-4-methoxybenzylidenyl)­indolin-2-one

Molecular Weight:
307.39 g·mol−1
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Alternative Distributors of [3-(3-tert-Butyl-4-methoxybenzylidenyl)­indolin-2-one]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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