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Tetrabenazine

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Formula: C19H27 N O3
CAS: 58-46-8
search Element: tetrabenazine

Identification

Structural Formula
Tetrabenazine
CAS:
58-46-8
EINECS:
200-383-6
Molecular Formula:
C19H27 N O3
MDL:
MFCD08461052
SMILES:
CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC
Synonym:
rubigen ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- (6ci,8ci) ; ro 1-9569 ; nsc 169886 ; 3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1h-pyrido[2,1-a]isoquinolin-2(11bh) ; tetrabenazine ; 9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2h-benzo[a]quinolizin-2-one ; (3r,11br)-rel- ; 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydropyrido[2,1-a]isoquinolin-2-one ; cis-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2h-benzo[a]quinolizin-2-one ; (?à)-tetrabenazine ; cis-2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bh-benzo[a]quinolizine ; nitoman ; nsc172187 ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis- ; 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-benzo[a]quinolizin-2-one ; 2h-benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3r,11br)-rel-


Description

Tetrabenazine is a potent inhibitor of vesicular monoamine uptake; depletes stores of serotonin, dopamine and noradrenalin. Binds with high affinity (IC50 = 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588
Aea.ltd
A91182
Aozeal Certified Standards (AOCS), Inc.
T0024.00
Inke S.A.
IS117351
Hangzhou Keying Chem Co., Ltd.
HKC3901560
Wanko Chemical Co., Ltd.
WC312936
Finetech Industry Limited
FIL3251300
Carbone Scientific Co., Ltd.
CS3641092
Xingrui Industry Co., Limited
XIL3771508
Capot Chemical Co., Ltd.
26005
BOC Sciences
BS156468
Leap Chem Co., Ltd
LC234702
Santa Cruz Biotechnology, Inc.
204338
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
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CAS equal suppliers

Tizanidine
Aozeal Certified Standards (AOCS), Inc.
T0032.00
Tetrabenazine Labeled d7
Santa Cruz Biotechnology, Inc.
sc-356121

Prices & Availability




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Properties for Tetrabenazine

Molecular Weight:
317.47 g·mol−1
Density:
1.12
Melting point:
128-130 °C C
Boiling point:
448.9°C at 760 mmHg
Flash point:
225.3°C
Solubility:
Soluble in ethanol (30 mM), DMSO (100 mM), water (hot), alcohol, and chloroform.
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Safety & Transport Information

Poison by subcutaneous and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
Risk Codes:
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
3249
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Alternative Distributors of [Tetrabenazine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Jinan Great Chemical Co., Ltd. | Watson International Ltd | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC. | Jinjiangchem Corporation | East Chemical Industry Co., Ltd. | Aopharm

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