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N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride

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Formula: C10H16N2 . 2HCl
CAS: 637-01-4

Identification

Structural Formula
N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride
CAS:
637-01-4
EINECS:
211-274-8
Molecular Formula:
C10H16N2 . 2HCl
MDL:
MFCD00012482
SMILES:
CN(C)C1=CC=C(C=C1)N(C)C.Cl.Cl
Synonym:
nnnn-tetramethyl-p-phenylendiamine 2hcl ; tmpd (hydrochloride) ; tetramethyl-p-phenylenediamine 2 hcl ; tetramethylpphenylenediaminedihcl ; wurster-reagent ; wurster's reagent ; n,nntetramethyl-p-phenylenediamine ; tmpd ; wurster's reagent dihydrochloride ; tmpd dihydrochloride


Description

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. TMPD undergoes one-electron oxidation by the heme peroxidase higher oxidation states (compounds I and II) producing a highly colored product that absorbs at 611 nm. Thus, the stoichiometry of oxidation is 2 moles of TMPD oxidized per mole of hydroperoxide reduced by the peroxidase. The extinction coefficient of the oxidized TMPD at 611 nm is 12,200.2 TMPD is also used for the detection of peroxidases on polyacrylamide gels.


Suppliers

Santa Cruz Biotechnology, Inc.
205528
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Prices & Availability




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Properties for N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride

Molecular Weight:
237.17 g·mol−1
Melting point:
222-224 °C(lit.)
Physical Description:
off white to gray powder
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
Hazard Classes:
6.1(a)
Hazard Symbols:
Xi, Xn
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Store at RT.
RID/ADR certification :
2811
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Alternative Distributors of [N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | BOC Sciences | ABCR GmbH & Co. KG | Pfaltz & Bauer, Inc. | Share Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Molekula GmbH | Yongyi Chemicals Group Co., Ltd. | Matrix Scientific | Discovery Fine Chemicals Limited | Chengdu Qiaofeng Technological Development Co., Ltd. | Amadis Chemical Co., Ltd. | Aakash Chemicals & Dye-Stuffs, Inc. | East Chemical Industry Co., Ltd.

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