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Tetrandrine

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Formula: C38H42N2O6
CAS: 518-34-3
search Element: tetrandrine

Identification

Structural Formula
Tetrandrine
CAS:
518-34-3
EINECS:
Molecular Formula:
C38H42N2O6
MDL:
MFCD08689909
SMILES:
CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Synonym:
conba ; tetrandrin ; d-tetrandrine ; tetrandrine ; sinomeninea ; hanfangchin a ; fanchinine ; (+)-tetrandrine ; trandrine ; jinake


Description

Tetrandrine is a calcium channel protein inhibitor. Tetrandrine blocks the L-type (IC50= 0.3-8 µM) and T-type (IC50= 2.5-20 µM) calcium channels. It is also a potent blocker of the Ca2+-activated K+ channel (Kd= 0.2 µM).


Suppliers

Ambeed, Inc.
A256378
Chengdu Pufeide Biotech. Co., Ltd
CPB3631452
Indofine Chemical Co, Inc.
06-029
CSNpharm, Inc.
CSN16381
Sigma-Aldrich International GmbH
SI3521056
Carbone Scientific Co., Ltd.
CS308924
Pharmacore Co., Limited
PL253759
AK Scientific, Inc.
AS209627
Simagchem Corporation
SC231693
BOC Sciences
BS132396
Santa Cruz Biotechnology, Inc.
201492
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CAS equal suppliers

D-Tetrandrine
Acinopeptide Co., Ltd.
A286572
D-Tetrandrine
Aecochem Corp.
AC182546
D-Tetrandrine
Leap Chem Co., Ltd
LC234702
D-Tetrandrine
Hangzhou J&H Chemical Co., Ltd.
HJC4031612
D-Tetrandrine
Gihi Chemicals Co., Limited
GCL3511404
D-Tetrandrine
Skyrun Industrial Co., Ltd.
SI3511053
D-Tetrandrine
Haihang Industry Co., Ltd.
HI3381014
D-Tetrandrine
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
D-Tetrandrine
Xingrui Industry Co., Limited
XIL3771508
D-Tetrandrine
H&Z Industry Co.,Ltd
HIC2601040
D-Tetrandrine
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588

Prices & Availability




Data is processed


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Properties for Tetrandrine

Molecular Weight:
622.75 g·mol−1
Density:
~1.17 g/cm3 (Predicted)
Melting point:
219-222 °C(lit.)
Boiling point:
~710.55° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO, and ether. Insoluble in water.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [Tetrandrine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Santec Chemicals Corp. | East Chemical Industry Co., Ltd. | Chengdu Biopurify Phytochemicals Ltd. | China Risesun Group Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanxi Zishan Natural Technology Co., Ltd. | BOC Sciences | Chengdu Conut Intl. Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Jinan Haohua Industry Co., Ltd.

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MSDS:
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