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Tramiprosate

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Formula: C3H9NO3S
CAS: 3687-18-1
search Element: tramiprosate
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Identification

Structural Formula
Tramiprosate
CAS:
3687-18-1
EINECS:
222-977-4
Molecular Formula:
C3H9NO3S
MDL:
MFCD00008225
SMILES:
C(CN)CS(=O)(=O)O
Synonym:
3-sulfopropylamine ; 3 aps ; homotaurine ; nsc 77071 ; 3-aminopropan-1-sulfonsure ; alzhemed ; nc 758 ; tramiprosate ; homotaurin ; 3-aminopropiosulfonic acid


Description

Sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (Aβ) and maintains Aβ in a non-fibrillar form. Decreases brain amyloid plaque load by 30%, increases tau polymerization and is brain penetrant. Decreases Aβ42-induced neuronal death and inhibits amyloid deposition in vitro. Also a GABA analog that protects against the convulsant and cytotoxic activity of kainic acid in vivo.


Suppliers

Ambeed, Inc.
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CSNpharm, Inc.
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Santa Cruz Biotechnology, Inc.
204353
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Prices & Availability




Data is processed


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Properties for Tramiprosate

Molecular Weight:
139.17 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
293 °C (dec.)(lit.)
Boiling point:
295.91° C (Predicted)
Solubility:
Soluble in water (50 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
Store at 0-5°C
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Alternative Distributors of [Tramiprosate]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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