Identification
Molecular Formula:
C1 0 H7 F3 N2
SMILES:
FC(F)(F)C1=C(C=CC=C1)N1C=CN=C1
Synonym:
1-(2-trifluoromethylphenyl)imidazole ; i-(2-trifluoromethylphenyl)imidazole ; 1-[2-(trifluoromethyl)phenyl]-1h-imidazole ; trim ; 1-(2-trifluoromethylphenyl)imidazole, 98+% ; 2-(1h-imidazol-1-yl)benzotrifluoride, 1-(1h-imidazol-1-yl)-2-(trifluoromethyl)benzene ; 1-[2-(trifluoromethyl)phenyl]-1h-imidazole98% ; 1-[2-(trifluoromethyl)phenyl]-1h-imidazole 98% ; 1-(alpha,alpha,alpha-trifluoro-o-tolyl)-imidazole
Description
TRIM is an inhibitor of NOS1 (nNOS) and NOS2 (iNOS) with IC50 values of 28.2 μM and 27.0 μM, respectively. Studies involving mice suggest that TRIM is a useful tool in determining the roles of NOS in the central nervous system. In addition, TRIM inhibits acetic acid induced abdominal constriction of mice, thus displaying its antinociceptive ability. Furthermore, TRIM interferes with the binding between arginine and tetrahydrobiopterin.
Suppliers
Xingrui Industry Co., Limited
XIL116464
Santa Cruz Biotechnology, Inc.
200353
Dayang Chem (Hangzhou) Co.,Ltd.
DC124496
CAS equal suppliers
1-(2-(Trifluoromethyl)phenyl)imidazole
Haihang Industry Co., Ltd.
HI494014820
1-(2-(Trifluoromethyl)phenyl)imidazole
Zehao Industry Co., Ltd.
ZI456013680
1-[2-(Trifluoromethyl)phenyl]imidazole
TCI Chemicals (India) Pvt. Ltd.
T2982
1-[2-(Trifluoromethyl)phenyl]imidazole
Capot Chemical Co., Ltd.
6489
1-(2-Trifluoromethylphenyl)imidazole, 98+%
Alfa (A Johnson Matthey Company)
A403212096
1-[2-(trifluoromethyl)phenyl]-1h-imidazole
Indofine Chemical Co, Inc.
09-2158
1-[2-(Trifluoromethyl)phenyl]-1H-imidazole
Key Organics Limited
PS-7992
1-(2-(Trifluoromethyl)-phenyl)-(1H)-imidazole
Hangzhou J&H Chemical Co., Ltd.
HJC976539060
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
Downloads
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Properties for TRIM
Molecular Weight:
212.17 g·mol−1
Boiling point:
75 °C 0,02mm
Flash point:
75 °C/0.025mm
Solubility:
Soluble in ethanol (~14 mg/ml), DMSO (30 mg/ml), DMF (~14 mg/ml), PBS(pH7.2) (~0.9 mg/ml), dichloromethane, 0.1 N HCl (6 mg/ml), 0.1 N NaOH (2 mg/ml), and slightly soluble in water (5 mg/ml).
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Hazard Statements
GHS03
Harmful
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
Not used
with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization
Safety & Transport Information
Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical adviceS36 - Wear suitable protective clothing
Hazard Classes:
irritant, light sensitive
Hazard Symbols:
Xi
Storage temperature :
2-8°C
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Alternative Distributors of [TRIM]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
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Element: 
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