Triptolide | CAS 38748-32-2 | Chemical-Suppliers

Element: triptolide

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C-S » Chemicals » triptolide-PX71710

Identification

Triptolide

CAS:

38748-32-2

EINECS:

Molecular Formula:

C₂₀H₂₄O₆

MDL:

MFCD00210565

SMILES:

CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C(C5C[C@H]7[C@]4([C@@H]2O)O7)COC6=O)C

Synonym:

triptolide95% ; nsc 163062 ; triptonide(p) ; triptolide ; triptolide(p) ; triptolide(pg490) ; pg490 ; triptolid ; triptolide, >=98% ; triptolide tlc

Description

Triptolide is a diterpene triepoxide antibiotic originally isolated from extracts of the herb Tripterygium wilfordii Hook F (TWHF). Triptolide has been shown to induce apoptosis of T lymphocytes by activating caspases, displaying an increase of DEVD-cleavable caspase activity correlated with the apoptosis. The proliferation of rheumatoid synovial fibroblasts characteristic of rheumatoid arthritis was similarly suppressed by treatment with Triptolide through an increase in caspase-3 activity. Cytokine gene expression in blood lymphocytes and T-cells are also suppressed by Triptolide, blocking the transcriptional activation of purine-box/antigen receptor response element/nuclear factor of activated T-cells (NF-AT) and of NF-kappaB.

Suppliers

Chengdu Pufeide Biotech. Co., Ltd

CPB3301320

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Indofine Chemical Co, Inc.

06-1285

Evonik ( formerly Wilshire Technologies, Inc. )

E4801920

CSNpharm, Inc.

CSN19415

Finetech Industry Limited

FIL2501000

Pharmacore Co., Limited

PL230690

Acinopeptide Co., Ltd.

A220440

Simagchem Corporation

SC210630

Xingrui Industry Co., Limited

XIL2901160

Zehao Industry Co., Ltd.

ZI240720

BOC Sciences

BS120360

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

200122

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CAS equal suppliers

Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one,3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-,(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-

Gihi Chemicals Co., Limited

GCL135459541836

Prices & Availability

Data is processed

Properties for Triptolide

Molecular Weight:

360.4 g·mol−1

Density:

1.48 g/cm³

Melting point:

226-227 °C

Boiling point:

601.7 °C at 760 mmHg

Solubility:

DMSO: soluble

Safety & Transport Information

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes

Storage temperature :

2-8°C

Alternative Distributors of [Triptolide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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