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Zoniporide dihydrochloride

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Formula: C17H16N6O.2HCl
CAS: 241800-97-5

Identification

Structural Formula
Zoniporide dihydrochloride
CAS:
241800-97-5
EINECS:
Molecular Formula:
C17H16N6O.2HCl
MDL:
SMILES:
C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)N=C(N)N.Cl.Cl
Synonym:
[1-(quinolin-5-yl)-5-cyclopropyl-1h-pyrazole-4-carbonyl]guanidine dihydrochloride ; zoniporide dihydrochloride


Description

Zoniporide dihydrochloride is a NHE-1 (sodium-hydrogen exchanger isoform-1) inhibitor that displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE-1, human NHE-2 and rat NHE-3 respectively). Zoniporide dihydrochloride inhibits NHE-1 dependent 22Na+ uptake in vitro (IC50=14 nM.)


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Santa Cruz Biotechnology, Inc.
204423
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Properties for Zoniporide dihydrochloride

Molecular Weight:
393.27 g·mol−1
Boiling point:
584.3° C at 760 mmHg (Predicted) (tautomer)
Solubility:
Soluble in water (10 mM), and DMSO (100 mM).
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Safety & Transport Information

Storage temperature :
Desiccate at -20 °C
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Alternative Distributors of [Zoniporide dihydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Mol File:
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MSDS:
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