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Cdk1/5 Inhibitor

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Formula: C9H7N5
CAS: 40254-90-8
search Element: inhibitor cdk1
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Identification

Structural Formula
Cdk1/5 Inhibitor
CAS:
40254-90-8
EINECS:
Molecular Formula:
C9H7N5
MDL:
MFCD04038461
SMILES:
C1=CC2=NC3=C(NN=C3N=C2C=C1)N
Synonym:
nsc 693868 ; 1h-pyrazolo[3,4-b]quinoxalin-3-amine ; 3-amino-1h-pyrazolo[3,4-b]quinoxaline ; 3-aminopyrazolo[3,4-b]quinoxaline ; 1h-pyrazolo[3,4-b]quinoxalin-3-amine(9ci)


Description

Cdk1/5 Inhibitor is a 3-amino substituted pyrazoloquinoxaline compound that acts as a selective inhibitor of Cdk1 and Cdk5 (IC50 = 600 nM for Cdk1/cyclin B and 400 nM for Cdk5/p25. Cdk1/5 Inhibitor is also shown to inhibit GSK-3β with (IC50 > 10 μM). Cdk1/5 Inhibitor does not inhibit Cdc25 phosphatase activity (IC50 > 10 μM).


Suppliers

Santa Cruz Biotechnology, Inc.
202094
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CAS equal suppliers

1H-Pyrazolo[3,4-b]quinoxalin-3-amine
Leap Chem Co., Ltd
LC25927776

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Data is processed


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Properties for Cdk1/5 Inhibitor

Molecular Weight:
185.19 g·mol−1
Density:
1.57 g/cm3
Melting point:
292-293°C (ethanol )
Boiling point:
522.8 °C at 760mmHg
Flash point:
303 °C
Solubility:
Soluble in DMSO (5 mg/ml).
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Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
Safety Codes:
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
Store at +4 °C
RID/ADR certification :
UN 2811 6.1 / PGIII
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Alternative Distributors of [Cdk1/5 Inhibitor]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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