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16,16-dimethyl Prostaglandin A1

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Formula: C22H36O4
CAS: 41692-24-4
search Element: prostaglandin dimethyl
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Identification

Structural Formula
16,16-dimethyl Prostaglandin A1
CAS:
41692-24-4
EINECS:
Molecular Formula:
C22H36O4
MDL:
SMILES:
CCCCC(C)(C)[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O
Synonym:
16,16-dimethyl prostaglandin a1 ; 9-oxo-15r-hydroxy-16,16-dimethyl-prosta-10,13e-dien-1-oic acid


Description

16,16-dimethyl Prostaglandin A1 is a metabolism resistant analog of PGA1 that inhibits the viral replication in both HSV and HIV-1 infection systems in vitro at concentrations that do not adversely alter cellular DNA synthesis. The ID50 values for HSV-1 strains in vero cells and human foreskin fibroblasts are 3.8-5.6 µg/ml and 4.6-7.3 µg/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 µg/ml.


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Santa Cruz Biotechnology, Inc.
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Properties for 16,16-dimethyl Prostaglandin A1

Molecular Weight:
364.52 g·mol−1
Boiling point:
~488.14° C (Predicted)
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Alternative Distributors of [16,16-dimethyl Prostaglandin A1]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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