(±)12-HETE | CAS 71030-37-0 | Chemical-Suppliers

Element: plusmn hete

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C-S » Chemicals » hete-PX81008

Identification

(±)12-HETE

CAS:

71030-37-0

EINECS:

Molecular Formula:

C₂₀H₃₂ O₃

MDL:

MFCD00065826

SMILES:

CCCCC/C=CCC(/C=CC=C/C/C=C/CCCC(=O)O)O

Synonym:

(r)-12-hete ; (+/-)12-hete ; 12-hydroxyeicosatetraenoicacid ; 10,14-eicosatetraenoicacid,12-hydroxy-,(e,z,z,z)-8 ; (+/-)12-hydroxy-5z,8z,10e,14z-eicosatetraenoic acid ; (+/-)12-hydroxyeicosa-5z,8z,10e,14z-tetraenoic acid ; 5,8,10,14-eicosatetraenoic acid, 12-hydroxy-, (e,z,z,z)- ; (5z,8z,10e,14z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid ; (5z,8z,10e,14z)-12-hydroxy-5,8,10,14-icosatetraenoic acid ; (5e,8z,10z,14z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid ; 5,8,10,14-eicosatetraenoicacid, 12-hydroxy-, (e,z,z,z)- ; (5z,8z,10e,14z)-12-hydroxy-5,8,10,14-eicosatetraenoicacid ; 12-hete ; 12-hydroxy-5,8,10,14-eicosatetraenoic acid ; 12-hydroxyeicosatetraenoic acid ; 5,8,10,14-eicosatetraenoicacid, 12-hydroxy-, (5z,8z,10e,14z)-

Description

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers. It aggregates neutrophils with an EC50 value of 40 nM.