Prostaglandin F2α

Prostaglandin F_2α is a major uterine prostaglandin that has been shown to cause contraction of vascular, bronchial, intestinal, myometrial smooth muscle, and to inhibit adipocyte differentiation. Research has demonstrated that PGF_2α inhibits nitric oxide production by the uterine tissue, increases uterine contractility, and displays potent luteolytic activity. Prostaglandin F_2α is an activator of PGF_2αR.