UCH-L1 Inhibitor | CAS 668467-91-2

Element: inhibitor

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C-S » Chemicals » uch-inhibitor-PX83579

Identification

UCH-L1 Inhibitor

CAS:

668467-91-2

EINECS:

Molecular Formula:

C₁₇H₁₁Cl₃N₂O₃

MDL:

MFCD09037562

SMILES:

CC(=O)ON=C1C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl

Synonym:

1H-Indole-2,3-dione, 5-chloro-1-[(2,5-dichlorophenyl)methyl]-, 3-(O-acetyloxime)

Description

UCH-L1 Inhibitor is an isatin O-acyl oxime compound reported to act as a potent, reversible, competitive, and active site-directed inhibitor of UCH-L1 with greater selectivity over UCH-L3. For a UCH-L3 inhibitor, please see sc-204370.

Additionally, UCH-L1 Inhibitor has been shown to increase proliferation of UCH-L1 expressing tumor cell line SH-SY5Y. Potentially useful for studying the roles of UCH-L1 in cancer, Parkinson's disease, and other neurological disorders. Permeability may vary from cell type to cell type.